Question

Alanine scanning mutagenesis was introduced to inhibit this protein's binding to its namesake receptor. Deficiency in this protein is a childhood symptom of Prader–Willi syndrome, so injections (0[2])of a version of this protein (0[1])are a common treatment for it and for both SHOX deficiency (20[1])and Turner syndrome. This protein is involved (0[1])in a negative feedback loop in which it stimulates IGF-1 (20[1])production in the (20[1])liver. (20[1]0[1])The most abundant (20[1])cell type (20[1])in the anterior (0[2])(*) pituitary gland secretes this protein in short pulses (10[1]0[1])that are regulated by (10[1])somatostatin and (10[1])somatocrinin. (10[1]0[2])Until growth (0[1])plate fusion, (10[1])greater abundance (10[2])of this protein increases height. (10[3])For (10[1])10 points, (10[4]0[1])name this hormone (10[1])whose deficiency (10[2])causes short stature. (10[3])■END■ (10[12]0[2])

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Summary