Question
Substituting a methyl in this molecule with a bromine yields an analog that is tagged in to monitor the cell cycle. Beads coated in oligomers of this molecule are used to isolate mRNA. An azide-containing mimic of this molecule was the earliest HIV drug. This common nucleobase is distinguished by two carbonyl groups and one methyl group. This is the first nucleobase in the name of a promoter motif that appears (*) 30 bases upstream of the transcription start site. This nucleobase creates kinks in DNA when it dimerizes due to UV radiation. This is the second DNA nucleobase in the start codon and the first one in stop codons. For 10 points, name this pyrimidine that is mimicked by uracil and pairs with adenine. ■END■
ANSWER: thymine [or thymidine or deoxythymidine or thymidine monophosphate or azidothymidine or Thy; prompt on T or or TMP or dT or dTMP or AZT or TATA box] (The analog in the lead-in is BrdU. dT oligomers hybridize with mRNAs' poly(A) tails. The HIV drug is AZT. The promoter motif is the TATA box.)
<Science - Biology>
= Average correct buzz position
Buzzes
| Player | Team | Opponent | Buzz Position | Value |
|---|---|---|---|---|
| Sophia Guo | Thomas Jefferson B | Northmont | 56 | 0 |
| Matthew Yang | Centennial B | Uni School of Nashville A | 73 | 10 |
| Jonathan Ouyang | Uni of Illinois Laboratory | Adlai E. Stevenson B | 76 | 10 |
| Snehan Saroch | Russell | Northside College Prep | 91 | 10 |
Summary
| Tournament | Edition | Exact Match? | TUH | Conv. % | Power % | Neg % | Average Buzz |
|---|---|---|---|---|---|---|---|
| 2025 PACE NSC | 06/07/2025 | Y | 4 | 75% | 0% | 0% | 80.00 |