Question
Deactivation of a component in this technique enables "modulation" via either "interference" or "activation," yielding variants that append "i" or "a" to the name of this technique. George M. Church joked that his lab "[focuses] on inventions" when Feng Zhang did not receive the Nobel for this technique, despite holding its patent. This technique is the most prominent successor of TALENs ("talons") and Fok·I-based ZFNs. This technique acts near a length 8-to-10 seed region and an adjacent (*) PAM sequence. This technique, which is derived from a microbial antiviral mechanism, uses tracr·RNA in guide RNA to bring an endonuclease to a DNA target. For 10 points, name this technique that uses Cas proteins to edit the genome. ■END■
ANSWER: CRISPR/Cas9 [or CRISPR/Cas or CRISPRi or CRISPRa or CRISPRi/a or CRISPRmod or clustered regularly interspaced short palindromic repeats; prompt on answers describing gene editing]
<Science - Biology>
= Average correct buzz position
Buzzes
| Player | Team | Opponent | Buzz Position | Value |
|---|---|---|---|---|
| Wyatt Johnson | Solon | Lexington | 77 | 0 |
| Rochan Saireddy | Lambert B | Thomas Jefferson C | 86 | 0 |
| Samin Asif | Seven Lakes | North Quincy | 111 | 10 |
| Aadi Pudasaini | Lexington | Solon | 115 | 10 |
| Nathan Liang | Thomas Jefferson C | Lambert B | 115 | 10 |
Summary
| Tournament | Edition | Exact Match? | TUH | Conv. % | Power % | Neg % | Average Buzz |
|---|---|---|---|---|---|---|---|
| 2025 PACE NSC | 06/07/2025 | Y | 1 | 100% | 0% | 0% | 115.00 |