Question

DTT reduces these bonds (20[1])by forming a six-membered ring. A primary cellular use of selenium is by enzymes that break these bonds (20[1])like GPx. (20[1])These bonds form when the antioxidant glutathione (20[1])is oxidized in the cytoplasm. Beta-mercaptoethanol (20[2]0[1])breaks these (20[1])bonds before SDS-PAGE ("S-D-S page") and was used to break them in Anfinsen's (0[1])experiment. The enzyme (0[1])(*) PDI in the endoplasmic reticulum (10[1])rearranges these bonds, which hold together the light and heavy chains of antibodies. Irreversible denaturation occurs when these (10[1])covalent bonds are broken. These covalent bonds, which are formed by the thiol groups of two cysteines ("SIS-teenz"), stabilize the tertiary structure of proteins. For 10 points, name these covalent bonds that join two S atoms. ■END■ (10[2])

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