Question

Signal-sensing domains that alter the rate of this process are found in some of its namesake "factors" that bind to DNA. For 10 points each:
[10e] Name this process in which DNA is used as a template to produce RNA.
ANSWER: transcription [or tx]
[10m] Transcription factors like STAT are activated when a tyrosine residue in their signal-sensing domain undergoes this chemical modification due to the action of a Janus kinase.
ANSWER: phosphorylation [accept word forms such as phosphorylate; prompt on adding a phosphate group]
[10h] The ability of transcription factors to bind to DNA can be sterically blocked by histone acetylation, an example of this process that controls chromatin accessibility. The ATP-dependent form of this process translocates nucleosomes.
ANSWER: chromatin remodeling [or nucleosome remodeling; prompt on histone modification]
<Science - Biology>

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